{"id":9543,"date":"2024-11-30T10:24:52","date_gmt":"2024-11-30T10:24:52","guid":{"rendered":"https:\/\/adelaiye-ogala-laboratory.com\/?page_id=9543"},"modified":"2025-01-07T17:10:57","modified_gmt":"2025-01-07T17:10:57","slug":"tej-sharma-phd","status":"publish","type":"page","link":"https:\/\/adelaiye-ogala-laboratory.com\/?page_id=9543","title":{"rendered":"Tej Sharma, PhD"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"9543\" class=\"elementor elementor-9543\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dc40793 e-flex e-con-boxed e-con e-parent\" data-id=\"dc40793\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-8309c8c e-con-full e-flex e-con e-child\" data-id=\"8309c8c\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-c838bbd elementor-widget elementor-widget-image\" data-id=\"c838bbd\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"683\" height=\"1024\" src=\"https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-683x1024.jpg\" class=\"attachment-large size-large wp-image-9520\" alt=\"\" srcset=\"https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-683x1024.jpg 683w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-200x300.jpg 200w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-768x1152.jpg 768w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-1024x1536.jpg 1024w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-1365x2048.jpg 1365w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-2000x3000.jpg 2000w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-1000x1500.jpg 1000w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-1800x2700.jpg 1800w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-373x560.jpg 373w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-600x900.jpg 600w, https:\/\/adelaiye-ogala-laboratory.com\/wp-content\/uploads\/2024\/11\/sharma_tej_6648-scaled.jpg 1707w\" sizes=\"(max-width: 683px) 100vw, 683px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ab125de e-con-full e-flex e-con e-child\" data-id=\"ab125de\" data-element_type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-9298ff2 elementor-widget elementor-widget-text-editor\" data-id=\"9298ff2\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<h3 style=\"text-align: left;\"><b>Postdoctoral Associate<\/b><\/h3><p style=\"text-align: left;\"><a href=\"mailto: tejsharm@buffalo.edu\" target=\"_blank\" rel=\"noopener\">Contact<\/a> | <a href=\"https:\/\/scholar.google.com\/citations?user=_Y7D8gQAAAAJ&amp;hl=en&amp;oi=ao\" target=\"_blank\" rel=\"noopener\">Publications<\/a><\/p><p style=\"language: en-US; margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; text-align: left; direction: ltr; unicode-bidi: embed; mso-line-break-override: none; word-break: normal; punctuation-wrap: hanging;\"><span style=\"font-size: 14.0pt; font-family: Georgia; mso-ascii-font-family: Georgia; mso-fareast-font-family: +mn-ea; mso-bidi-font-family: +mn-cs; mso-fareast-theme-font: minor-fareast; mso-bidi-theme-font: minor-bidi; color: #203864; mso-color-index: 4; mso-font-kerning: 12.0pt; language: en-US; font-weight: bold; mso-style-textfill-type: solid; mso-style-textfill-fill-themecolor: accent1; mso-style-textfill-fill-color: #203864; mso-style-textfill-fill-alpha: 100.0%; mso-style-textfill-fill-colortransforms: lumm=50000;\">Qualifications: <\/span><span style=\"font-size: 14.0pt; font-family: Georgia; mso-ascii-font-family: Georgia; mso-fareast-font-family: +mn-ea; mso-bidi-font-family: +mn-cs; mso-fareast-theme-font: minor-fareast; mso-bidi-theme-font: minor-bidi; color: #203864; mso-color-index: 4; mso-font-kerning: 12.0pt; language: en-US; mso-style-textfill-type: solid; mso-style-textfill-fill-themecolor: accent1; mso-style-textfill-fill-color: #203864; mso-style-textfill-fill-alpha: 100.0%; mso-style-textfill-fill-colortransforms: lumm=50000;\">PhD Computational Biophysics <\/span><\/p><p style=\"text-align: left;\"><!--StartFragment--> <!--EndFragment--><\/p><p style=\"margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed; word-break: normal; text-align: left;\"><span style=\"font-size: 14.0pt; font-family: Georgia; mso-ascii-font-family: Georgia; mso-fareast-font-family: +mn-ea; mso-bidi-font-family: +mn-cs; mso-fareast-theme-font: minor-fareast; mso-bidi-theme-font: minor-bidi; color: #203864; mso-color-index: 4; mso-font-kerning: 12.0pt; language: en-US; font-weight: bold; mso-style-textfill-type: solid; mso-style-textfill-fill-themecolor: accent1; mso-style-textfill-fill-color: #203864; mso-style-textfill-fill-alpha: 100.0%; mso-style-textfill-fill-colortransforms: lumm=50000;\">Skills:\u00a0<\/span><span style=\"color: #003366;\">Expert in MD simulations (AMBER, NAMD, and GROMACS), molecular docking (AutoDock Vina), and protein structure prediction (RosettaFold and AlphaFold). Proficient in next-generation sequencing (NGS) data processing using tools such as STAR, BWA, SAMtools, and Bowtie, along with workflow automation using NextFlow, nf-core, and Snakemake. Experienced in gene expression analysis with HTSeq, DESeq2, and edgeR, as well as genomic data manipulation with BEDTools. Skilled in data visualization (IGV, UCSC Genome Browser). Analyzing bulk RNA sequencing, single-cell RNA sequencing, ATAC-seq, proteomics, and DNA methylation data. Expertise in variant calling (Mutect2, Strelka, Control-FREEC, SnpEff and so on). Strong knowledge of high-performance computing (HPC) environments and cloud platforms for large-scale data analysis. Proficient in containerization technologies (Docker and Singularity) for reproducible workflows. Extensive experience in applying machine learning techniques, including regression models, random forests, and clustering (t-SNE, PCA, K-means), as well as deep learning frameworks like Keras and PyTorch. Programming skills include R, Python, Bash, Perl, and SQL, with a strong emphasis on data cleaning, wrangling, and visualization.<\/span><\/p><p style=\"margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed; word-break: normal; text-align: left;\"><span style=\"font-size: 14pt; font-family: Georgia; color: #003366;\">\u00a0<\/span><\/p><p style=\"margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed; word-break: normal; text-align: left;\"><span style=\"text-align: center; font-weight: var( --e-global-typography-text-font-weight ); font-size: 14pt; font-family: Georgia; color: #203864; font-style: italic;\">\u201d<\/span><span style=\"color: #203864; font-family: Georgia; font-size: 14pt; font-style: italic; text-align: center; font-weight: var( --e-global-typography-text-font-weight );\">With a robust background in computational biophysics, I am committed to advancing the understanding of disease mechanisms, particularly in oncology, to identify novel therapeutic targets. By harnessing advanced bioinformatics pipelines, state-of-the-art computational tools, machine learning, and deep learning techniques, I aim to elucidate complex protein interactions, integrate multi-omics datasets, and spearhead innovative drug discovery efforts to improve patient outcomes.\u201d\u00a0<\/span><\/p><p style=\"margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed; word-break: normal; text-align: left;\"><span style=\"color: #203864; font-family: Georgia; font-size: 14pt; font-style: italic; text-align: center; font-weight: var( --e-global-typography-text-font-weight );\">\u00a0<\/span><\/p><p style=\"margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed; word-break: normal; text-align: left;\"><span style=\"font-size: 16.0pt; font-family: Georgia; mso-ascii-font-family: Georgia; mso-fareast-font-family: +mn-ea; mso-bidi-font-family: +mn-cs; mso-fareast-theme-font: minor-fareast; mso-bidi-theme-font: minor-bidi; color: #203864; mso-color-index: 4; mso-font-kerning: 12.0pt; language: en-US; font-weight: bold; mso-style-textfill-type: solid; mso-style-textfill-fill-themecolor: accent1; mso-style-textfill-fill-color: #203864; mso-style-textfill-fill-alpha: 100.0%; mso-style-textfill-fill-colortransforms: lumm=50000;\">Fun Fact<\/span><\/p><p style=\"margin-top: 0pt; margin-bottom: 0pt; margin-left: 0in; direction: ltr; unicode-bidi: embed; word-break: normal; text-align: left;\"><span style=\"color: #002060; font-family: Georgia; font-size: 14pt; text-align: center; font-weight: var( --e-global-typography-text-font-weight );\">When I\u2019m not diving into datasets, I\u2019m buried in books\u2014exploring topics like AI, economics, history, and domestic and international politics. By day, I analyze data; by night, I devour debates!<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7ff9e6d e-flex e-con-boxed e-con e-parent\" data-id=\"7ff9e6d\" data-element_type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-10f6a60 elementor-widget elementor-widget-text-editor\" data-id=\"10f6a60\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>&lt;- <a href=\"https:\/\/adelaiye-ogala-laboratory.com\/?page_id=50\">Back<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Postdoctoral Associate Contact | Publications Qualifications: PhD Computational Biophysics Skills:\u00a0Expert in MD simulations (AMBER, NAMD, and GROMACS), molecular docking (AutoDock Vina), and protein structure prediction (RosettaFold and AlphaFold). Proficient in next-generation sequencing (NGS) data processing using tools such as STAR, BWA, SAMtools, and Bowtie, along with workflow automation using NextFlow, nf-core, and Snakemake. Experienced in gene expression analysis with HTSeq, DESeq2, and edgeR, as well as genomic data manipulation with BEDTools. Skilled in data visualization [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9543","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Tej Sharma, PhD - Adelaiye-Ogala Laboratory<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/adelaiye-ogala-laboratory.com\/?page_id=9543\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tej Sharma, PhD - Adelaiye-Ogala Laboratory\" \/>\n<meta property=\"og:description\" content=\"Postdoctoral Associate Contact | Publications Qualifications: PhD Computational Biophysics Skills:\u00a0Expert in MD simulations (AMBER, NAMD, and GROMACS), molecular docking (AutoDock Vina), and protein structure prediction (RosettaFold and AlphaFold). Proficient in next-generation sequencing (NGS) data processing using tools such as STAR, BWA, SAMtools, and Bowtie, along with workflow automation using NextFlow, nf-core, and Snakemake. Experienced in gene expression analysis with HTSeq, DESeq2, and edgeR, as well as genomic data manipulation with BEDTools. 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